Published on 09/23/2021 by Dr. med. Christian Gersch
Phenolic acids are often broken down by bacteria in the intestine before they are absorbed into the body and thus become bioavailable in the first place. Bifidobacteria and lactobacilli, in particular, play a major role, for example in hydroxycinnamic acid or feral acid. Bifidobacteria and lactobacilli are typical inhabitants of the large intestine. They are considered to be "healthy" old. This could be due to the fact that they are very supportive in providing us with polyphenols. So it would be an imaginable tactic to not only include polyphenols but to investigate the quantification of the microbiome. If it turns out that not enough bifidobacteria and lactobacilli are present, then it would make sense to first increase their numbers and to push back less favorable bacteria such as the clostridia species. If phenolic acids are absorbed, they can be detected in the blood. That distributes them throughout the body, with the liver and kidneys constantly filtering out, breaking down, and excreting phenols such as gallic acid, so that blood levels are only maintained for a few hours.
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